Overview
Advancing antibody function through smart design.
Transforming a promising antibody into a successful therapeutic which delivers all its potential requires precision engineering. By fine-tuning affinity, specificity, half-life, effector functions (e.g., ADCC, CDC), and manufacturability, antibody engineering ensures clinical performance, regulatory readiness, and commercial scalability.
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Advancing antibody function through smart design.
Techniques like Fc modification, glycoengineering, and humanization unlock therapeutic potential while minimizing immunogenicity and maximizing consistency across patient populations.
Fusion Antibodies builds smarter biologics through precision engineering—designed for therapeutic impact.
Each service page gives you the detail, evidence and practical route forward—without making this overview do all the talking.
Fusion Antibodies provides antibody humanization services that help biotechnology and pharmaceutical companies reduce immunogenicity while preserving the affinity, specificity and functionality of their lead antibodies. Since 2012, we have completed 300 antibody humanization projects while 100% successfully maintaining function and affinity and no reported immunogenicity issues following our humanization strategy.
Antibody species conversion is a critical step when transitioning therapeutic or diagnostic antibodies originally developed in human, mouse or rabbit into veterinary formats suitable for cat, dog, horse, pig or cattle. This process ensures compatibility with the target species’ immune system, minimizing immunogenicity and enhancing efficacy.
Explore the full spectrum of antibody reformatting techniques—from chimerisation to Multivalent Variants; tailored for research, diagnostics, and therapeutics.
Bispecific antibodies are engineered therapeutic molecules designed to simultaneously bind two distinct antigens or epitopes. This dual targeting capability enables powerful and differentiated mechanisms of action, including immune cell redirection, enhanced tumor selectivity, dual checkpoint inhibition, and coordinated modulation of multiple disease pathways.
Enhance effector function, extend half-life or silence activity with Fc region modifications designed by our expert team.
At Fusion Antibodies, we recognize that the biophysical and biochemical properties of antibodies critically influence the safety, efficacy, and manufacturability of biologic therapeutics. That’s why we begin every project with a forward-thinking approach—leveraging our deep expertise in sequence optimization to streamline your path to the clinic.
Fusion’s affinity maturation platform combines natural somatic hypermutation with advanced structural modelling to introduce targeted mutations and evaluate molecular interactions, resulting in antibody variants with enhanced binding affinity and improved stability.
When programmes move between disconnected providers, knowledge is diluted. At Fusion, the same scientific context can travel from target and lead generation through engineering, characterisation and supply.
Bring us a target, an existing antibody or a difficult development decision.
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